{"id":149,"date":"2026-01-26T19:21:12","date_gmt":"2026-01-26T19:21:12","guid":{"rendered":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/?page_id=149"},"modified":"2026-01-26T19:21:55","modified_gmt":"2026-01-26T19:21:55","slug":"trendsetter","status":"publish","type":"page","link":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/trendsetter\/","title":{"rendered":"Trendsetter"},"content":{"rendered":"\n

A Python script that implements the classifier Trendsetter<\/em> of Mughal and DeGiorgio (2019) for classifying genomic regions as neutral, hard sweep, or soft sweep using the spatial distribution of summary statistics around a test site.<\/p>\n\n\n\n

Results of genome scans for selective sweeps using Trendsetter<\/em> as applied to seven 1000 Genomes Project populations in Mughal and DeGiorgio (2019).
[Click to download scan results<\/a>]\n\n\n\n

Please cite the following manuscript if using this software:<\/strong>
MR Mughal, M DeGiorgio (2019) Localizing and classifying adaptive targets with trend filtered regression. Molecular Biology and Evolution<\/em> 36:252-270.<\/p>\n\n\n\n[Click to download manual<\/a>]
[Click to download software (300 MB download including example data)<\/a>]\n\n\n\n

On a UNIX system, extract the compressed files using the command
tar -xzvf trendsetter.tar.gz
Change directory to trendsetter using a command such as
cd trendsetter
The trendsetter.py script will be located in the trendsetter directory<\/p>\n\n\n\n

Software history<\/strong>
May 11, 2018 – Uploaded version 1.0 of the software and manual
August 31, 2018 – Updated software to include classifier calibration<\/p>\n","protected":false},"excerpt":{"rendered":"

A Python script that implements the classifier Trendsetter of Mughal and DeGiorgio (2019) for classifying genomic regions as neutral, hard sweep, or […]<\/p>\n","protected":false},"author":101,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"normal-width-container","site-content-style":"boxed","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-149","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/wp-json\/wp\/v2\/pages\/149","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/wp-json\/wp\/v2\/users\/101"}],"replies":[{"embeddable":true,"href":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/wp-json\/wp\/v2\/comments?post=149"}],"version-history":[{"count":2,"href":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/wp-json\/wp\/v2\/pages\/149\/revisions"}],"predecessor-version":[{"id":151,"href":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/wp-json\/wp\/v2\/pages\/149\/revisions\/151"}],"wp:attachment":[{"href":"https:\/\/faculty.eng.fau.edu\/degiorgiogroup\/wp-json\/wp\/v2\/media?parent=149"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}