Microfluidic testing of cell deformability and vasoocclusion
We develop microfluidic mimics of blood vasculature and spleen to measure cell deformability in malaria, sickle cell disease, and artificial blood
ASK-Modulated Electro-deformation: Cell Mechanics and Fatigue
We integrate ASK-modulated electro-deformation in microfluidic platforms to measure mechanical degradation and failure in circulating cells due to cyclic shear stresses and cyclic hypoxia
Point-of-Care Disease Monitoring
We combine microelectronics, microfluidics and electrical impedance sensing techniques to develop portable flow cytometry device, and in vitro blood testing tools for the measurements of sickle cell vaso-occlusion and cell sickling kinetics
Organ-on-a-Chips
We employ cell cultures in microfluidic environment to reconstitute the structure, biological function, and the dynamic interactions in human organs and tissues that are difficult to study such as placental barrier and neuromuscular junctions